hepatocellular carcinoma in a sheep

Authors

h nourani

i karimi,

abstract

at necropsy of a five-year-old sheep, a pear shaped, lobular yellow-brownish mass measuring about 12 ×15 × 20 cm was found to involve the right hepatic lobe. microscopic examination revealed two trabecularand solid patterns of neoplastic hepatocytes. in solid pattern, there were numerous tumoral giant cells thatcontain one or more large hyperchromatic bizarre-shaped nuclei scattered among clusters of neoplastichepatocytes. in addition, mitotic figures, dilated sinusoids and large vascular spaces filled with red bloodcells were observed in some sections. based on gross and histopathologic characteristics, the mass wasdiagnosed as hepatocellular carcinoma

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Journal title:
iranian journal of veterinary research

Publisher: shiraz university

ISSN 1728-1997

volume 8

issue 4 2007

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